SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
SARS-CoV-2 protein expression studies in the Drosophila heart suggest a cause of COVID-19-associated cardiac pathology via interaction of virus Nsp6 with the host MGA/MAX complex disrupting glycolysis and cardiac mitochondrial function.
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03986-6 |