Coexistent ARID1A-PIK3CA mutations are associated with immune-related pathways in luminal breast cancer

Abstract Up to 40% of luminal breast cancer patients carry activating mutations in the PIK3CA gene. PIK3CA mutations commonly co-occur with other mutations, but the implication of this co-occurrence may vary according to the specific genes involved. Here, we characterized a subgroup of luminal breas...

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Bibliographic Details
Main Authors: Liat Anabel Sinberger, Tamar Zahavi, Amir Sonnenblick, Mali Salmon‐Divon
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48002-x