A “double hit” murine model for schizophrenia shows alterations in the structure and neurochemistry of the medial prefrontal cortex and the hippocampus

A “double hit” murine model for schizophrenia shows alterations in the structure and neurochemistry of the medial prefrontal cortex and the hippocampus

Both alterations in neurodevelopment and aversive experiences during childhood and adolescence seem important risk factors for schizophrenia. Animal models reproducing these alterations mimic some of the symptoms, constituting a valid approach to study the etiopathology of this disorder. Among these...

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Bibliographic Details
Main Authors: Javier Gilabert-Juan, Maria Belles, Ana Rosa Saez, Hector Carceller, Sara Zamarbide-Fores, Maria Dolores Moltó, Juan Nacher
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Neurobiology of Disease
Subjects:
Schizophrenia
Animal model
Inhibitory neurotransmission
Adult neurogenesis
Interneuron
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113002027

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http://www.sciencedirect.com/science/article/pii/S0969996113002027

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