Purification of GFRα1+ and GFRα1– Spermatogonial Stem Cells Reveals a Niche-Dependent Mechanism for Fate Determination

Purification of GFRα1+ and GFRα1– Spermatogonial Stem Cells Reveals a Niche-Dependent Mechanism for Fate Determination

Summary: Undifferentiated spermatogonia comprise a pool of stem cells and progenitor cells that show heterogeneous expression of markers, including the cell surface receptor GFRα1. Technical challenges in isolation of GFRα1+ versus GFRα1– undifferentiated spermatogonia have precluded the comparative...

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Bibliographic Details
Main Authors: Alina Garbuzov, Matthew F. Pech, Kazuteru Hasegawa, Meena Sukhwani, Ruixuan J. Zhang, Kyle E. Orwig, Steven E. Artandi
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111730557X

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http://www.sciencedirect.com/science/article/pii/S221367111730557X

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