Metabolic profiling of parthenolide: Characterized by bioactive organosulfur compounds involving in hydrogen sulfide regulation

Metabolic profiling of parthenolide: Characterized by bioactive organosulfur compounds involving in hydrogen sulfide regulation

Parthenolide (PA) shows promising therapeutic effect on ulcerative colitis and colorectal cancer, and can ameliorate colon inflammation in a gut microbiota-dependent manner. In the present study, an effective UHPLC-QTOF-MS method aided by rat intestinal microbiota biotransformation was applied to ch...

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Bibliographic Details
Main Authors: Qiqi Zhou, Lu Gao, Yannan Ji, Xiaoding Zhang, Ningning Shi, Jia Liu, Pengbo Tang, Haixia Gao, Changhong Huo
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Arabian Journal of Chemistry
Subjects:
Parthenolide
Metabolite
UHPLC-QTOF-MS
Hydrogen sulfide
Bioactivity
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223004665

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http://www.sciencedirect.com/science/article/pii/S1878535223004665

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