Feasibility of randomizing Danish citizens aged 65–79 years to high-dose quadrivalent influenza vaccine vs. standard-dose quadrivalent influenza vaccine in a pragmatic registry-based setting: rationale and design of the DANFLU-1 Trial

Feasibility of randomizing Danish citizens aged 65–79 years to high-dose quadrivalent influenza vaccine vs. standard-dose quadrivalent influenza vaccine in a pragmatic registry-based setting: rationale and design of the DANFLU-1 Trial

Abstract Background High-dose influenza vaccines provide better protection against influenza infection than standard-dose in persons aged 65 years and above; however, in most countries, high-dose vaccines are not widely implemented. Assessing the relative effectiveness of high-dose compared to stand...

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Bibliographic Details
Main Authors: Niklas Dyrby Johansen, Daniel Modin, Joshua Nealon, Sandrine Samson, Camille Salamand, Carsten Schade Larsen, Brian L. Claggett, Scott D. Solomon, Martin J. Landray, Gunnar H. Gislason, Lars Køber, Jens Ulrik Stæhr Jensen, Pradeesh Sivapalan, Lasse Skafte Vestergaard, Palle Valentiner-Branth, Tyra Grove Krause, Tor Biering-Sørensen
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Pilot and Feasibility Studies
Subjects:
Randomized controlled trial
Pragmatic
Influenza
Vaccine
Registry
Feasibility
Online Access:https://doi.org/10.1186/s40814-022-01044-w

Internet

https://doi.org/10.1186/s40814-022-01044-w

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