Humoral immune response induced with dengue virus-like particles serotypes 1 and 4 produced in silkworm

Highlights Dengue virus-like particles for serotype 1 and serotype 4 (DENV-LPs/1 and DENV-LPs/4) were produced in silkworm. Heparin-binding assay by ELISA and ITC showed that DENV-LPs/1 and DENV-LPs/4 contain Envelope Domain III. DENV-LPs/1 and DENV-LPs/4 showed affinity to sera from human dengue pa...

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Bibliographic Details
Main Authors: Doddy Irawan Setyo Utomo, Sabar Pambudi, Enoch Y. Park
Format: Article
Language:English
Published: SpringerOpen 2022-01-01
Series:AMB Express
Subjects:
Online Access:https://doi.org/10.1186/s13568-022-01353-6