Transcriptional regulation of an evolutionary conserved intergenic region of CDT2-INTS7.

In the mammalian genome, a substantial number of gene pairs (approximately 10%) are arranged head-to-head on opposite strands within 1,000 base pairs, and separated by a bidirectional promoter(s) that generally drives the co-expression of both genes and results in functional coupling. The significan...

Full description

Bibliographic Details
Main Authors: Hiroki Nakagawa, Moe Tategu, Rieko Yamauchi, Kaori Sasaki, Sota Sekimachi, Kenichi Yoshida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2194621?pdf=render