Breakthrough infection evokes the nasopharyngeal innate immune responses established by SARS-CoV-2–inactivated vaccine

Breakthrough infection evokes the nasopharyngeal innate immune responses established by SARS-CoV-2–inactivated vaccine

Nasopharyngeal immune responses are vital for defense against SARS-CoV-2 infection. Although vaccination via muscle immunization has shown a high efficacy in reducing severity and death in COVID-19 infection, breakthrough infection frequently happens because of mutant variants and incompletely estab...

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Bibliographic Details
Main Authors: Xiaomeng He, Yingyin Cao, Yanmei Lu, Furong Qi, Haiyan Wang, Xuejiao Liao, Gang Xu, Biao Yang, Junhua Ma, Dapeng Li, Xian Tang, Zheng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
breakthrough infection
mucosal immunity
single-cell RNA sequencing
innate immune memory
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1181121/full

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