Discovery of a Metabolic Signature Predisposing High Risk Patients with Mild Cognitive Impairment to Converting to Alzheimer’s Disease

Discovery of a Metabolic Signature Predisposing High Risk Patients with Mild Cognitive Impairment to Converting to Alzheimer’s Disease

Assessing dementia conversion in patients with mild cognitive impairment (MCI) remains challenging owing to pathological heterogeneity. While many MCI patients ultimately proceed to Alzheimer’s disease (AD), a subset of patients remain stable for various times. Our aim was to characterize the plasma...

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Bibliographic Details
Main Authors: Yi-Long Huang, Chao-Hsiung Lin, Tsung-Hsien Tsai, Chen-Hua Huang, Jie-Ling Li, Liang-Kung Chen, Chun-Hsien Li, Ting-Fen Tsai, Pei-Ning Wang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
mild cognitive impairment
untargeted metabolomics
plasma
feature selection
Online Access:https://www.mdpi.com/1422-0067/22/20/10903

Internet

https://www.mdpi.com/1422-0067/22/20/10903

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