Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and ‘inflammaging'

Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and ‘inflammaging'

Aging is considered a state of low grade inflammation, occurring in the absence of any overt infection often referred to as ‘inflammaging'. Maintaining intestinal homeostasis may be a target to extend a healthier status in older adults. Here, we report that even in healthy older men low grade b...

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Bibliographic Details
Main Authors: Annette Brandt, Anja Baumann, Angélica Hernández-Arriaga, Finn Jung, Anika Nier, Raphaela Staltner, Dragana Rajcic, Christian Schmeer, Otto W. Witte, Barbara Wessner, Bernhard Franzke, Karl-Heinz Wagner, Amélia Camarinha-Silva, Ina Bergheim
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Redox Biology
Subjects:
Aging
Endotoxin
Nitric oxide
Intestinal permeability
Microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722003007

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http://www.sciencedirect.com/science/article/pii/S2213231722003007

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