Computational model of integrin adhesion elongation under an actin fiber.

Cells create physical connections with the extracellular environment through adhesions. Nascent adhesions form at the leading edge of migrating cells and either undergo cycles of disassembly and reassembly, or elongate and stabilize at the end of actin fibers. How adhesions assemble has been address...

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Bibliographic Details
Main Authors: Samuel Campbell, Michelle C Mendoza, Aravind Rammohan, Matthew E McKenzie, Tamara C Bidone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1011237