BRAF Inhibitors in Metastatic Colorectal Cancer and Mechanisms of Resistance: A Review of the Literature

BRAF Inhibitors in Metastatic Colorectal Cancer and Mechanisms of Resistance: A Review of the Literature

Metastatic colorectal cancer (mCRC) with mutated BRAF exhibits distinct biological and molecular features that set it apart from other subtypes of CRC. Current standard treatment for these tumors involves a combination of chemotherapy (CT) and VEGF inhibitors. Recently, targeted therapy against BRAF...

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Bibliographic Details
Main Authors: Patricia Guerrero, Víctor Albarrán, María San Román, Carlos González-Merino, Coral García de Quevedo, Jaime Moreno, Juan Carlos Calvo, Guillermo González, Inmaculada Orejana, Jesús Chamorro, Íñigo Martínez-Delfrade, Blanca Morón, Belén de Frutos, María Reyes Ferreiro
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
BRAF
inhibitors
resistance
colorectal cancer
Online Access:https://www.mdpi.com/2072-6694/15/21/5243

Internet

https://www.mdpi.com/2072-6694/15/21/5243

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