HX008: a humanized PD-1 blocking antibody with potent antitumor activity and superior pharmacologic properties

Through reactivating tumor-infiltrating lymphocytes, therapeutics targeting programmed cell death protein 1 (PD-1) demonstrate impressive clinical efficacy in the treatment of multiple cancers. In this report, we characterize HX008, a humanized IgG4S228P anti-PD-1 monoclonal antibody with an enginee...

Full description

Bibliographic Details
Main Authors: Jibin Zhang, Ying Huang, Gan Xi, Faming Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:mAbs
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2020.1724751