Hereditary Optic Neuropathies: A Systematic Review on the Interplay between Biomaterials and Induced Pluripotent Stem Cells

Hereditary Optic Neuropathies: A Systematic Review on the Interplay between Biomaterials and Induced Pluripotent Stem Cells

Hereditary optic neuropathies (HONs) such as dominant optic atrophy (DOA) and Leber Hereditary Optic Neuropathy (LHON) are mitochondrial diseases characterized by a degenerative loss of retinal ganglion cells (RGCs) and are a cause of blindness worldwide. To date, there are only limited disease-modi...

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Bibliographic Details
Main Authors: Miguel Ladero, Jose Alberto Reche-Sainz, M. Esther Gallardo
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Bioengineering
Subjects:
iPSCs
differentiation
transplantation
RGCs
optic neuropathies
LHON
Online Access:https://www.mdpi.com/2306-5354/11/1/52

Internet

https://www.mdpi.com/2306-5354/11/1/52

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