Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits

Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits

DNA methylation (DNAm) and microRNAs (miRNAs) have been implicated in a wide-range of human diseases. While often studied in isolation, DNAm and miRNAs are not independent. We analyzed associations of expression of 283 miRNAs with DNAm at >400K CpG sites in whole blood obtained from 3565 individu...

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Bibliographic Details
Main Authors: Tianxiao Huan, Michael Mendelson, Roby Joehanes, Chen Yao, Chunyu Liu, Ci Song, Anindya Bhattacharya, Jian Rong, Kahraman Tanriverdi, Joshua Keefe, Joanne M. Murabito, Paul Courchesne, Martin G. Larson, Jane E. Freedman, Daniel Levy
Format: Article
Language:English
Published: Taylor & Francis Group 2020-02-01
Series:Epigenetics
Subjects:
dna methylation
microrna
mir-eqtm
eqtm
complex traits
age at menarche
Online Access:http://dx.doi.org/10.1080/15592294.2019.1640547

Internet

http://dx.doi.org/10.1080/15592294.2019.1640547

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