Artificial placenta support of extremely preterm ovine fetuses at the border of viability for up to 336 hours with maintenance of systemic circulation but reduced somatic and organ growth

Introduction: Artificial placenta therapy (APT) is an experimental life support system to improve outcomes for extremely preterm infants (EPI) less than 1,000 g by obviating the need for pulmonary gas exchange. There are presently no long-term survival data for EPI supported with APT. To address thi...

Full description

Bibliographic Details
Main Authors: Haruo Usuda, Hideyuki Ikeda, Shimpei Watanabe, Shinichi Sato, Erin L. Fee, Sean W. D. Carter, Yusaku Kumagai, Yuya Saito, Tsukasa Takahashi, Yuki Takahashi, Shinichi Kawamura, Takushi Hanita, Masatoshi Saito, Atsuo Kikuchi, Mahesh A. Choolani, Nobuo Yaegashi, Matthew W. Kemp
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1219185/full