Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM
Cryo-electron microscopy reveals the structure and activation mechanism of MrgD, a member of the Mas-related G protein-coupled receptor family of GPCRs involved in itch and nociception.
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-07-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03668-3 |