Harnessing HEK293 cell-derived exosomes for hsa-miR-365a-3p delivery: Potential application in hepatocellular carcinoma therapy

Harnessing HEK293 cell-derived exosomes for hsa-miR-365a-3p delivery: Potential application in hepatocellular carcinoma therapy

Hepatocellular carcinoma (HCC) is the most frequent form of liver malignancy, and curing it is very challenging. Restoring tumor suppressor microRNAs could trigger the initiation of cellular anticancer mechanisms. Exosomes are nanosized biocarriers capable of fusing with cell membranes and deliverin...

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Bibliographic Details
Main Authors: Armita Ghotaslou, Arezou Azizsoltani, Kaveh Baghaei, Effat Alizadeh
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
MiR-365a-3p mimic
Cell cycle
ROS
Exosome
HepG2
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024053647

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http://www.sciencedirect.com/science/article/pii/S2405844024053647

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