Activation of TCA cycle restrains virus-metabolic hijacking and viral replication in mouse hepatitis virus-infected cells

Abstract Background One of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused coronavirus disease 2019 (COVID-19) pandemic and threatened worldwide. However, therapy for COVID-19 has rarely been proven to possess specific efficacy. As the virus relies on host metab...

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Bibliographic Details
Main Authors: Sang R. Lee, Jeong Yeon Roh, Jihoon Ryu, Hyun-Jin Shin, Eui-Ju Hong
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-021-00740-z