The lncRNA HCG4 regulates the RIG-I-mediated IFN production to suppress H1N1 swine influenza virus replication

The lncRNA HCG4 regulates the RIG-I-mediated IFN production to suppress H1N1 swine influenza virus replication

Influenza A virus (IAV) non-structural protein 1 (NS1) is a virulence factor that allows the virus to replicate efficiently by suppressing host innate immune responses. Previously, we demonstrated that the serine (S) at position 42 of NS1 in H1N1 swine influenza virus (SIV) is a critical residue in...

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Bibliographic Details
Main Authors: Jinghua Cheng, Jie Tao, Benqiang Li, Ying Shi, Huili Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
swine influenza virus
NS1 protein
lncRNA
IFN
RIG-I ubiquitination
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1324218/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1324218/full

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