Residue-Specific Message Encoding in CD40-Ligand

Summary: CD40-Ligand (CD40L)-CD40 interaction regulates immune responses against pathogens, autoantigens, and tumor and transplantation antigens. Single amino acid mutations within the 115–155 amino acids stretch, which is responsible for CD40L functions, result in XIgM syndrome. We hypothesize that...

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Bibliographic Details
Main Authors: Aditya Yashwant Sarode, Mukesh Kumar Jha, Shubhranshu Zutshi, Soumya Kanti Ghosh, Hima Mahor, Uddipan Sarma, Bhaskar Saha
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220306337