TREK channel activation suppresses migraine pain phenotype

TREK channel activation suppresses migraine pain phenotype

Summary: Activation and sensitization of trigeminal ganglia (TG) sensory neurons, leading to the release of pro-inflammatory peptides such as calcitonin gene-related peptide (CGRP), are likely a key component in migraine-related headache induction. Reducing TG neuron excitability represents therefor...

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Bibliographic Details
Main Authors: Pablo Ávalos Prado, Arnaud Landra-Willm, Clément Verkest, Aurore Ribera, Anne-Amandine Chassot, Anne Baron, Guillaume Sandoz
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
pharmacology
biological sciences
neuroscience
behavioral neuroscience
Sensory neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009299

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http://www.sciencedirect.com/science/article/pii/S2589004221009299

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