mNSCs overexpressing Rimkla transplantation facilitates cognitive recovery in a mouse model of traumatic brain injury

mNSCs overexpressing Rimkla transplantation facilitates cognitive recovery in a mouse model of traumatic brain injury

Summary: N-acetyl aspartyl-glutamate (NAAG) is easily inactivated for the hydrolysis of NAAG peptidase on the surface of glial cells, thereby losing its endogenous neuroprotective effect after traumatic brain injury. In this study, lentiviral vectors were used to over express/knock out NAAG syntheta...

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Bibliographic Details
Main Authors: Tongjie Ji, Ying Pang, Meng Cheng, Rui Wang, Xu Chen, Chunyu Zhang, Min Liu, Jing Zhang, Chunlong Zhong
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Neurosurgery
Clinical neuroscience
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223019909

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http://www.sciencedirect.com/science/article/pii/S2589004223019909

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