polysaccharides protect renal function and affect the TGF-/Smad signaling pathway in streptozotocin-induced diabetic rats

Objectives The objective was to observe the effects of Astragalus polysaccharides on diabetes and on regulation of the TGF-β/Smad signaling pathway. Methods A type 2 diabetic rat model was established with a high-fat diet in combination with low-dose streptozotocin (35 mg/kg). Astragalus polysacchar...

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Bibliographic Details
Main Authors: Xue Meng, Mingmin Wei, Dong Wang, Xiaohan Qu, Kun Zhang, Nan Zhang, Xinjian Li
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520903612