Biomechanical and biochemical assessment of YB-1 expression in A375 melanoma cell line: Exploratory study

Malignant melanoma is the most lethal form of skin cancer. Y-box binding protein 1 (YB-1) plays a prominent role in mediating metastatic behavior by promoting epithelial-to-mesenchymal transition (EMT). Migratory melanoma cells exhibit two major migration modes: elongated mesenchymal or rounded amoe...

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Bibliographic Details
Main Authors: Anna Cykowska, Ulf Krister Hofmann, Aadhya Tiwari, Corinna Kosnopfel, Rosa Riester, Marina Danalache
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Molecular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmmed.2023.1050487/full