Increased histone citrullination in juvenile idiopathic arthritis

Increased histone citrullination in juvenile idiopathic arthritis

ObjectivePosttranslational modifications (PTMs) of proteins are crucial for regulating various biological processes. However, protein alteration via PTMs, and consequently, the creation of new epitopes, can induce abnormal autoimmune responses in predisposed individuals. Immunopathogenesis of severa...

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Bibliographic Details
Main Authors: Zuzana Parackova, Irena Zentsova, Hana Malcova, Dita Cebecauerova, Anna Sediva, Rudolf Horvath
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Medicine
Subjects:
juvenile idiopathic arthritis
citrullination
histone
neutrophil
NETosis
peptidyl arginine deiminases (PAD)
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.971121/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.971121/full

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