Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization.

Stress is a major risk factor for depression and anxiety. One of the effects of stress is the (over-) activation of the hypothalamic-pituitary-adrenal (HPA) axis and the release of stress hormones such as glucocorticoids (GCs). Chronically increased stress hormone levels have been shown to have detr...

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Bibliographic Details
Main Authors: Kelly Van Looveren, Michiel Van Boxelaere, Zsuzsanna Callaerts-Vegh, Claude Libert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226753