A Novel Approach for the Simultaneous Analysis of Common and Rare Variants in Complex Traits
Genome-wide association studies (GWAS) have been successful in detecting common genetic variants underlying common traits and diseases. Despite the GWAS success stories, the percent trait variance explained by GWAS signals, the so called “missing heritability” has been, at best, modest. Also, the pr...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-01-01
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Series: | Bioinformatics and Biology Insights |
Online Access: | https://doi.org/10.4137/BBI.S8852 |