Mtb-specific CD27low CD4 T cells as markers of lung tissue destruction during pulmonary tuberculosis in humans.

Mtb-specific CD27low CD4 T cells as markers of lung tissue destruction during pulmonary tuberculosis in humans.

Effector CD4 T cells represent a key component of the host's anti-tuberculosis immune defense. Successful differentiation and functioning of effector lymphocytes protects the host against severe M. tuberculosis (Mtb) infection. On the other hand, effector T cell differentiation depends on disea...

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Bibliographic Details
Main Authors: Irina Yu Nikitina, Natalya A Kondratuk, George A Kosmiadi, Rasul B Amansahedov, Irina A Vasilyeva, Vitaly V Ganusov, Irina V Lyadova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427145?pdf=render

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http://europepmc.org/articles/PMC3427145?pdf=render

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