Properties of resistant cells generated from lung cancer cell lines treated with EGFR inhibitors

<p>Abstract</p> <p>Background</p> <p>Epidermal growth factor receptor (EGFR) signaling plays an important role in non-small cell lung cancer (NSCLC) and therapeutics targeted against EGFR have been effective in treating a subset of patients bearing somatic EFGR mutation...

Full description

Bibliographic Details
Main Authors: Ghosh Gargi, Lian Xiaojun, Kron Stephen J, Palecek Sean P
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/12/95