Tumor necrosis factor induces tumor promoting and anti-tumoral effects on pancreatic cancer via TNFR1.

Tumor necrosis factor induces tumor promoting and anti-tumoral effects on pancreatic cancer via TNFR1.

Multiple activities are ascribed to the cytokine tumor necrosis factor (TNF) in health and disease. In particular, TNF was shown to affect carcinogenesis in multiple ways. This cytokine acts via the activation of two cell surface receptors, TNFR1, which is associated with inflammation, and TNFR2, wh...

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Bibliographic Details
Main Authors: Martin Chopra, Isabell Lang, Steffen Salzmann, Christina Pachel, Sabrina Kraus, Carina A Bäuerlein, Christian Brede, Ana-Laura Jordán Garrote, Katharina Mattenheimer, Miriam Ritz, Stefanie Schwinn, Carolin Graf, Viktoria Schäfer, Stefan Frantz, Hermann Einsele, Harald Wajant, Andreas Beilhack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3787053?pdf=render

Internet

http://europepmc.org/articles/PMC3787053?pdf=render

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