The evolved divergence of γ-secretase-susceptibility of homologous proteins Ngfrb and Nradd in zebrafish
Abstract Objective NGFR/p75NTR and NRADD/NRH proteins are closely related structurally and are encoded by genes that arose from a duplication event early in vertebrate evolution. The transmembrane domain (TMD) of NGFR is cleaved by γ-secretase but there is conflicting data around the susceptibility...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-12-01
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Series: | BMC Research Notes |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13104-021-05876-2 |