Multimodal in vivo Imaging of the Integrated Postnatal Development of Brain and Skull and Its Co-modulation With Neurodevelopment in a Down Syndrome Mouse Model

Multimodal in vivo Imaging of the Integrated Postnatal Development of Brain and Skull and Its Co-modulation With Neurodevelopment in a Down Syndrome Mouse Model

The brain and skeletal systems are intimately integrated during development through common molecular pathways. This is evidenced by genetic disorders where brain and skull dysmorphologies are associated. However, the mechanisms underlying neural and skeletal interactions are poorly understood. Using...

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Bibliographic Details
Main Authors: Sergi Llambrich, Rubèn González, Julia Albaigès, Jens Wouters, Fopke Marain, Uwe Himmelreich, James Sharpe, Mara Dierssen, Willy Gsell, Neus Martínez-Abadías, Greetje Vande Velde
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medicine
Subjects:
development
brain and skull integration
down syndrome
GTE-EGCG
μCT imaging
μMRI
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.815739/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.815739/full

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