ALDH1A1 in Cancers: Bidirectional Function, Drug Resistance, and Regulatory Mechanism

ALDH1A1 in Cancers: Bidirectional Function, Drug Resistance, and Regulatory Mechanism

Aldehyde dehydrogenases 1 family member A1(ALDH1A1) gene codes a cytoplasmic enzyme and shows vital physiological and pathophysiological functions in many areas. ALDH1A1 plays important roles in various diseases, especially in cancers. We reviewed and summarized representative correlative studies an...

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Bibliographic Details
Main Authors: Hanxun Yue, Zenan Hu, Rui Hu, Zeying Guo, Ya Zheng, Yuping Wang, Yongning Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
aldehyde dehydrogenases
cancer stem cell
carcinogenesis
drug resistance
hepatocellular carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.918778/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.918778/full

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