Promoter DNA methylation contributes to human β-defensin-1 deficiency in atopic dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by epidermal barrier dysfunction and dysregulation of innate and adaptive immunity. Epigenetic regulation of human β-defensin-1 (HBD-1) might be associated with a variety of defects in the innate immune system during AD pathogenesi...

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Bibliographic Details
Main Authors: Yoo-Hun Noh, Jaehyouk Lee, Seong Joon Seo, Soon Chul Myung
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2018.1458652