Optimization of Gonyautoxin1/4-Binding G-Quadruplex Aptamers by Label-Free Surface-Enhanced Raman Spectroscopy

Optimization of Gonyautoxin1/4-Binding G-Quadruplex Aptamers by Label-Free Surface-Enhanced Raman Spectroscopy

Nucleic acids with G-quadruplex (G4) structures play an important role in physiological function, analysis and detection, clinical diagnosis and treatment, and new drug research and development. Aptamers obtained using systematic evolution of ligands via exponential enrichment (SELEX) screening tech...

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Bibliographic Details
Main Authors: Yan Liu, Chengshun Jiang, Menghua Song, Yongbing Cao, Qiang Huang, Feng Lu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Toxins
Subjects:
surface-enhanced Raman spectroscopy
G-quadruplex aptamers
gonyautoxin
two-dimensional correlation spectroscopy
microscale thermophoresis
molecular dynamics
Online Access:https://www.mdpi.com/2072-6651/14/9/622

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https://www.mdpi.com/2072-6651/14/9/622

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