Thymoquinone-PLGA-PVA Nanoparticles Ameliorate Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulation of Inflammatory Cytokines and iNOS Signaling

Thymoquinone-PLGA-PVA Nanoparticles Ameliorate Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulation of Inflammatory Cytokines and iNOS Signaling

Pulmonary fibrosis is considered one of the most chronic interstitial illnesses which are not easily treated. thymoquinone’s (TQ) benefits are still partly problematic due to poor water solubility; therefore, it was loaded onto PLGA-PVA carriers. This study aimed to evaluate the potential...

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Bibliographic Details
Main Authors: Sultan A. M. Saghir, Naif A. Al-Gabri, Asmaa F. Khafaga, Nahla H. El-shaer, Khaled A. Alhumaidh, Mohamed F. Elsadek, Badreldin M. Ahmed, Daniyah M. Alkhawtani, Mohamed E. Abd El-Hack
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Animals
Subjects:
pulmonary fibrosis
plga
thymoquinone
il 10
tgf-β1
inos
ultrastructure
Online Access:https://www.mdpi.com/2076-2615/9/11/951

Internet

https://www.mdpi.com/2076-2615/9/11/951

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