Melatonin Reduces Apoptosis Resistance of Hepatocellular Carcinoma Cells by Inhibiting BMAL1

Purpose: This study aimed to explore the role and molecular mechanism of brain and muscle ARNT-like protein 1 (BMAL1) in hepatocellular carcinoma (HCC), and the effect of melatonin on BMAL1 expression and apoptosis of HCC cells. Methods: We mainly used immunohistochemistry, western blot, cck-8 assay...

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Bibliographic Details
Main Authors: Anqi Wang MMed, Bei Zhou MMed, Yue Zhu MD, Chaisheng Tan MMed, Jing Xu MD, Jie Cui PhD, Li Zhang MMed, Guoping Sun PhD
Format: Article
Language:English
Published: SAGE Publishing 2022-06-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/15347354221099539