FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast

FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast

Summary: FK506-binding protein with a molecular weight of 12 kDa (FKBP12) is a receptor of the immunosuppressive drugs, FK506 and rapamycin. The physiological functions of FKBP12 remain ambiguous because of its nonessentiality and multifunctionality. Here, we show that FKBP12 promotes the utilizatio...

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Bibliographic Details
Main Authors: Mayuki Sasaki, Shinichi Nishimura, Yoko Yashiroda, Akihisa Matsuyama, Hideaki Kakeya, Minoru Yoshida
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Biosynthesis
Biological sciences
Biochemistry
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222019319

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222019319

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