Identification of MEDAG and SERPINE1 Related to Hypoxia in Abdominal Aortic Aneurysm Based on Weighted Gene Coexpression Network Analysis

Identification of MEDAG and SERPINE1 Related to Hypoxia in Abdominal Aortic Aneurysm Based on Weighted Gene Coexpression Network Analysis

Purpose: Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease that often results in high mortality due to sudden rupture. This paper aims to explore potential molecular mechanisms and effective targeted therapies to prevent and delay AAA rupture.Methods: We downloaded two microarray da...

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Bibliographic Details
Main Authors: Biyun Teng, Chaozheng Xie, Yu Zhao, Qiu Zeng, Fangbiao Zhan, Yangyang Feng, Zhe Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Physiology
Subjects:
abdominal aortic aneurysm
hypoxia
weighted gene coexpression network analysis
gene set enrichment analysis
hub genes
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.926508/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.926508/full

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