Development and Validation of a Multi-Level Computational Protocol for Drug Repurposing in the Treatment of Bacterial Infections
Here, we report the optimization of a methodology using docking and virtual screening to identify novel clinical uses for already approved drugs. The molecular targets selected were MvfR and PqsD due to their crucial role in quorum sensing and biofilm formation and development. The FDA-approved subs...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
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| Series: | Chemistry Proceedings |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-4583/8/1/24 |