Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis

Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis

Abstract Background Myocardial fibrosis changes the structure of myocardium, leads to cardiac dysfunction and induces arrhythmia and cardiac ischemia, threatening patients’ lives. Electroacupuncture at PC6 (Neiguan) was previously found to inhibit myocardial fibrosis. Long non-coding RNAs (lncRNAs)...

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Bibliographic Details
Main Authors: Wenchuan Qi, Xiang Li, Yanrong Ren, Xueying Liu, Hongjuan Fu, Xiao Wang, Xiao Li, Jian Xiong, Qianhua Zheng, Dingjun Cai, Fanrong Liang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Chinese Medicine
Subjects:
Myocardial fibrosis
Electroacupuncture
lncRNA Miat
CTGF
TGF-β1
Heterodimer PPARG–RXRA
Online Access:https://doi.org/10.1186/s13020-022-00615-6

Internet

https://doi.org/10.1186/s13020-022-00615-6

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