Angelica gigas Nakai and Soluplus-Based Solid Formulations Prepared by Hot-Melting Extrusion: Oral Absorption Enhancing and Memory Ameliorating Effects.

Oral solid formulations based on Angelica gigas Nakai (AGN) and Soluplus were prepared by the hot-melting extrusion (HME) method. AGN was pulverized into coarse and ultrafine particles, and their particle size and morphology were investigated. Ultrafine AGN particles were used in the HME process wit...

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Bibliographic Details
Main Authors: Jingpei Piao, Jae-Young Lee, Jin Bae Weon, Choong Je Ma, Hyun-Jeong Ko, Dae-Duk Kim, Wie-Soo Kang, Hyun-Jong Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4411051?pdf=render