CTLA-4 suppresses hapten-induced contact hypersensitivity in atopic dermatitis model mice

Abstract Atopic dermatitis (AD) patients with skin barrier dysfunction are considered to be at a higher risk of allergic contact dermatitis (ACD), although previous studies showed that attenuated ACD responses to strong sensitizers in AD patients compared to healthy controls. However, the mechanisms...

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Bibliographic Details
Main Authors: Hiroe Tetsu, Kanako Nakayama, Taku Nishijo, Takuo Yuki, Masaaki Miyazawa
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35139-y