Epigenetic modulation of antitumor immunity for improved cancer immunotherapy

Epigenetic modulation of antitumor immunity for improved cancer immunotherapy

Abstract Epigenetic mechanisms play vital roles not only in cancer initiation and progression, but also in the activation, differentiation and effector function(s) of immune cells. In this review, we summarize current literature related to epigenomic dynamics in immune cells impacting immune cell fa...

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Bibliographic Details
Main Authors: Enyong Dai, Zhi Zhu, Shudipto Wahed, Zhaoxia Qu, Walter J. Storkus, Zong Sheng Guo
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Molecular Cancer
Subjects:
DNA methylation
Histone modifications
Epigenetic reprogramming
Metabolic reprogramming
Heterogeneity
Immune cells
Online Access:https://doi.org/10.1186/s12943-021-01464-x

Internet

https://doi.org/10.1186/s12943-021-01464-x

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