Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid

Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid

Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the deadliest infectious diseases worldwide. Multidrug and extensively drug-resistant strains are making disease control difficult, and exhausting treatment options. New anti-TB drugs bedaquiline (BDQ), delamanid (DLM) and p...

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Bibliographic Details
Main Authors: Paula J. Gómez-González, Joao Perdigao, Pedro Gomes, Zully M. Puyen, David Santos-Lazaro, Gary Napier, Martin L. Hibberd, Miguel Viveiros, Isabel Portugal, Susana Campino, Jody E. Phelan, Taane G. Clark
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98862-4

Internet

https://doi.org/10.1038/s41598-021-98862-4

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