Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways
Abstract Background Non-canonical Wnt pathways play important roles in liver fibrosis. Notum is a newly discovered inhibitor to Wnt proteins. This study was to investigate anti-fibrotic effects of Notum. Methods 53 patients with hepatitis B virus (HBV) infection as well as a cell co-culture system o...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-03-01
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| Series: | Biological Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40659-019-0217-8 |