Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways

Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways

Abstract Background Non-canonical Wnt pathways play important roles in liver fibrosis. Notum is a newly discovered inhibitor to Wnt proteins. This study was to investigate anti-fibrotic effects of Notum. Methods 53 patients with hepatitis B virus (HBV) infection as well as a cell co-culture system o...

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Bibliographic Details
Main Authors:	Wenting Li, Xiaolan Yu, Chuanlong Zhu, Zheng Wang, Zonghao Zhao, Yi Li, Yonghong Zhang
Format:	Article
Language:	English
Published:	BMC 2019-03-01
Series:	Biological Research
Subjects:	Notum Wnt signaling pathway HBV Liver fibrosis
Online Access:	http://link.springer.com/article/10.1186/s40659-019-0217-8

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