Model-based design and optimization of GSSR chromatography for peptide purification
Gradient with Steady State Recycle (GSSR) is a recently developed process for center-cut separation by solvent-gradient chromatography. The process comprises a multicolumn, open-loop system with cyclic steady-state operation that simulates a solvent gradient moving countercurrently with respect to t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-03-01
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| Series: | Digital Chemical Engineering |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772508122000722 |